BIOT 100 Biotechnology Practicum I (1 sem. hr.)
This hands-on course is part of an intern program in the Biology Department at TWU designed to provide instruction in general laboratory procedures and laboratory safety beyond that required during regular undergraduate laboratories. Performed tasks are evaluated and occur in the areas of animal husbandry, general laboratory maintenance, cell culture, histochemistry, light microscopy and protein chemistry (i.e. Western blotting, SDS-PAGE). Students will also acquire general instruction in Good Laboratory Practice (GLP) and Good Animal Practice (GAP).
Prerequisites/Co-requisites: BIOL 103/104/105 or BIOL 113/114. (0-0, 0-1)
BIOT 200/300/400 Biotechnology Practica II, III, IV (2 or 3 sem. hrs.)
Biotechnology Practica II–IV provide general and advanced intern experiences in industrial settings. BIOT 200 (2 sem. hrs.) is a requirement for entry to co-op placements and graduation. BIOT 300 and 400 (3 sem. hrs. each) are additional intern experiences providing exposure to advanced techniques and applications in biotechnology. The skills taught in each practicum vary depending on the industrial setting but should include some of the following techniques: mammalian tissue culture; monoclonal antibody production including cell fusion; hybridoma screening by ELISA and immunoblotting; fermentation microbiology and the operation of large-scale fermentation systems; insect cell culture and use of Baculovirus expression vectors to produce recombinant proteins; downstream processing and the recovery and purification of proteins, carbohydrates, lipids; freezing, freeze-drying and preservation of microorganisms, animal viruses, cell lines and hybridomas; high throughput screening strategies, diagnostic testing; methods in bioinformatics; and quality control procedures.
Cross-listed: BIOL 200/300
Prerequisite(s): BIOT 100.
BIOT 290 Introduction to Biotechnology (3 sem. hrs.)
This course reviews the role of modern biotechnology in plant, animal, and marine biology, microbiology, agriculture, the pharmaceutical industry and medicine. The course focuses on underlying technologies in biotechnology, how these technologies are implemented, together with public concerns and government guidelines and legislation.
Cross-listed: BIOL 290
Prerequisite(s): BIOL 103, 104, and 105 or BIOL 113, 114. (3-0 or 3-0)
BIOT 390 Biotechnology and Christian Theology (3 sem. hrs.)
This course is designed to untangle some of the actual or perceived dissonance between issues of biological science and Christian theology. Six major topics are addressed: (1) models, analogies and metaphors in science and Christian theology; (2) scientific and religious investigations of the biosphere; (3) defining human nature; (4) defining non-human nature; (5) caring for the earth; and (6) the biomedical revolution. The common threads among these topics are the tension between Christian faith and the findings of basic and applied biology (biotechnology), and the call to action required in a faith-based view of creation. As well as speaking from their own disciplines and background, the course instructors take part in panel discussions at the end of each of the six units to foster discussion and dialogue on the issues. Student participation is further encouraged by group projects in which the group must develop and present a position paper on an area that engenders dissonance between scientific and religious worldview perspectives.
Cross-listed: BIOL 390.
Prerequisite(s): BIOL 103, 104, and 105 or BIOL 113, 114; third year standing. (3-0 or 3-0)
BIOT 409 Thesis Preparation (1 sem. hr.)
Students choose a research topic for their senior thesis in consultation with biotechnology faculty. Selected readings and pertinent references to the topic are assigned. A final written report is presented consisting of a detailed thesis proposal with a review of the literature.
Cross-listed: BIOL 409.
Prerequisite(s): Advanced standing in biotechnology. (1-1; 0-0)
BIOT 410 Senior Thesis (2 sem. hrs.)
Research in a chosen area of biotechnology with a final written report and oral presentation of research findings.
Cross-listed: BIOL 410.
Prerequisite(s): BIOL 409, a related directed study in preparation, or instructor's consent. (0-0; 1-2)
BIOT 470 Genomics, Proteomics, Bioinformatics (3 sem. hrs.)
An overview of the interdisciplinary science of genomics, proteomics, and bioinformatics which applies the tools of information technology (computer hardware and software) to analyze biological data such as gene or protein sequences. This course examines the theory of bioinformatics as well as its practical application to biological problems using approaches such as BLAST searches, phylogenetics, and protein structure function analysis.
Cross-listed: BIOL 470.
Prerequisite(s): BIOL 223; BIOL/CHEM 372; and either 3 sem. hrs. of Computing Science or MATH 102. (0-0; 3-3-0)
BIOT 490 Advanced Biotechnology (3 sem. hrs.)
This capstone course in biotechnology considers the theoretical and practical aspects of implementing biotechnology, paying particular attention to current issues including: 1) technology transfer and commercialization; 2) patent protection in biotechnology; 3) Good Laboratory Practices (GLP); 4) Good Manufacturing Practices (Food and Drug Regulations, 2002 edition); 5) Good Clinical Practices (GCP); 6) Research Ethics Board guidelines; 7) validation studies; 8) downstream processing and the recovery of purified products; 9) novel developments in methodology. The course includes a seminar series by industry and regulatory experts and site visits to local biotechnology companies to assess how they have implemented and overcome obstacles to production and quality control.
Cross-listed: BIOL 490.
Prerequisite(s): BIOT 290. (0-0; 3-3)
This page contains official TWU academic program information.