This course is designed to untangle some of the actual or perceived dissonance between issues of biological science and Christian theology. Six major topics are addressed: (1) models, analogies, and metaphors in science and Christian theology; (2) scientific and religious investigations of the biosphere; (3) defining human nature; (4) defining non-human nature; (5) caring for the earth; and (6) the biomedical revolution. The common threads among these topics are the tension between Christian faith and the findings of basic and applied biology (biotechnology), and the call to action required in a faith-based view of creation. As well as speaking from their own disciplines and background, the course instructors take part in panel discussions at the end of each of the six units to foster discussion and dialogue on the issues. Student participation is encouraged by group projects that develop and present a position paper on an area that engenders dissonance between scientific and religious worldview perspectives.