This course offers an in-depth exploration of the study of grief, loss, and end-of-life care in the context of family systems, with a focus on the interconnection of familial, individual and relational dynamics. Emphasizing the role of culture, community, and family narratives, students will critically examine how diverse cultural, spiritual and faith rituals, beliefs, and practices shape responses to loss and mourning within family systems. This course covers models of grief and bereavement from a systemic lens, including complexities of anticipatory grief, ambiguous loss, and intergenerational loss. Special attention will be given to collaborative approaches in palliative care and working with interdisciplinary health teams to ensure ethical and appropriate care in these settings. Lastly, students will learn their roles as psychotherapists in supporting end-of-life conversations and learn how to integrate self of the therapist awareness to best address compassion fatigue and vicarious grief.